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retired doc's thoughts

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From the Annals of Internal Medicine:Oscar winners live longer-no,wait, maybe they don't

Posted Sunday September 17, 2006, 12:02 pm, Over one day old
A reanalysis of the evidence.Sylvestre,Huszti,and Hanley.Annals Internal Medicine,vol.145, no. 5, p. 361 ) that contradicted an earlier Annals'article that claimed Oscar winners live longer than their fellow actors.The abstract is available online.

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No pens or mugs allowed from Big Pharma at Stanford

Posted Friday September 15, 2006, 12:02 pm, Over one day old


Read No pens or mugs allowed from Big Pharma at Stanford (Links)

FDA offers recipe for proper mixing of aspirin and ibuprofen

Posted Monday September 11, 2006, 11:42 am, Over one day old
The American Heart Association recommends prophylactic aspirin for those who have a ten year heart attack risk of 10% or greater and the usually-much-more conservative U.S Preventive Services Task Force recommends aspirin for those who have a five year risk of 3 % or higher.

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Should the single digital FOBT be abandoned?

Posted Friday September 8, 2006, 11:42 am, Over one day old
The single FOBT test did badly, with a sensitivity of only 4.9% in detecting "advanced neoplasia" which was defined as tubular adenomas larger than 10 mm., adenomas with villous patterns, high grade dysplasia or invasive cancer. The six test kit did better with a sensitivity of 23.9%.

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Trial underway to test use of steroids in severe pneumonia

Posted Friday September 8, 2006, 11:42 am, Over one day old
In the August 14,2006 issue of Internal Medicine News we learn of reports that corticosteroids may reduce the morbidity and mortality of severe bacterial pneumonia.

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More on Quality Improvement Organizations"-another study fails to clearly show they work

Posted Wednesday September 6, 2006, 11:42 am, Over one day old
The accompanying editorial noted that although the study tended to show some rather small improvements in the group that received a quality improvement "intervention", other factors not adequately controlled for could also have been responsible study design and analysis left much to desire.

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Is interval training better for metabolic syndrome?

Posted Tuesday September 5, 2006, 11:42 am, Over one day old
But it is not clear how much exercise or what level of energy output is required to actually change the metabolic parameters of the metabolic syndrome.In fact, the literature on the effect of running on HDL is a bit murky as well.

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heuristics and statistics-we need and use both in medicine

Posted Monday September 4, 2006, 11:42 am, Over one day old
What the experienced docs seem to deal in mainly are heuristics. Statistical analysis is an essential element in clinical research but many of the decisions we make in the heat of the clinical battles that take place every day rely on mental processes that seem to have little to do with statistics.

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Houston V.A. physicians examine P4P data and find evidence of gaming and treating the chart

Posted Tuesday August 29, 2006, 11:42 am, Over one day old


Read Houston V.A. physicians examine P4P data and find evidence of gaming and treating the chart (Links)

The gabapentin story: "Medical education drives this market"

Posted Tuesday August 22, 2006, 12:22 pm, Over one day old
There are other aspects detailed by the authors including the use of "medical education" companies hired by P-D to ghost write articles and organize meetings, and supply various CME products which were basically advertisements for off-label use of gabapentin.

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